Building the Future Powered by Science



Transformative companies are built here.

Extraordinary founders are unlocking the power of science with technology, expanding the frontier of what’s possible to create new markets and build the next generation of category-defining companies.

Building at this frontier requires conviction, deep technical understanding, and the ability to recognize inflection points before the market does.

Breakout has spent more than a decade investing at this edge. We partner with exceptional founders scaling scientific innovation to build the breakout companies powering our future.
▶︎CYTOVALE

diagnosing immune-mediated diseases

CONVICTION FROM DAY ONE

We invest early and with conviction: in you, your vision, and your ability to land it.

Like your approach to science, our partnership is rigorous. We focus relentlessly on the inflection points that matter, bringing a disciplined and tailored approach to every company we back.

Join us
▶︎MODERN MEADOW

sustainable biofabrication

OPENING THE RIGHT DOORS

Breakout is embedded in the markets our founders need to win.

We maintain deep relationships with the corporates, strategic partners, and next-stage investors you will need to scale. Our catalytic network drives traction and helps reach milestones faster.

▶︎STRM.BIO

in vivo gene therapy

FRONTIER FOCUS ADVANTAGE

Biotech, tech-bio, deep tech, hard tech, chem tech… whatever you call it, we’ve been steeped in science-driven technology for over a decade. 

Our team of scientists and operators have the technical depth and commercial fluency to anticipate roadblocks and navigate complexity at this frontier.

OUR TEAMOUR TEAM
▶︎ECOVATIVE DESIGN

mycelium-grown materials

Breakout Companies

Scientific innovation changes what’s possible. Scaling innovation into breakout companies changes our future. 

Meet the companies delivering on the promise of science.
Our Portfolio

Noetik

Training foundation models to develop cancer immunotherapies

Epana Bio

Advancing autoimmune care with precision therapies

ZymoChem

Increasing performance chemical yields with biomanufacturing

Twelve

Transforming carbon dioxide emissions into useful chemicals
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Whether you've launched your company or are doing the heavy lifting to get to the starting line…

Let's Talk